Construction of 2,6-trans pyrans via Prins cyclization and its application towards the total synthesis of methyl sarcophytoate
Prins cyclization reaction involving a homoallylic alcohol with aldehyde is one of the most efficient methods to synthesize tetrahydropyran rings. However, due to the strong 1,3-diaxial interaction, the 2,6-cis tetrahydropyran moiety was formed preferably in most cases. The emphasis of this thesis i...
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| Format: | Thesis |
| Language: | English |
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2012
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| Online Access: | https://hdl.handle.net/10356/47588 |