Purification and characterization of a potent dendritic cell activator released by T cells
CD8+ T lymphocytes, during priming, can induce robust maturation of dendritic cells (DCs) in a CD40 independent manner by secreting licensing factor(s). I have isolated this so far elusive licensing factor and identified it as GM-CSF. Signaling through the GM-CSF receptor in ex-vivo purified DCs upr...
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| Format: | Thesis |
| Language: | English |
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2012
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| Online Access: | https://hdl.handle.net/10356/49515 |