Biophysical and structural studies of self-assembled liposome/E-peptide/DNA nanoparticles : correlation with gene delivery
Recently, novel DNA compaction agents, ε-oligo(L-lysines) and their branched α-amino-acid substituted derivatives, have been successfully tested as vectors for in vitro gene delivery. The present work exploits a number of newly developed ε-oligolysine-based peptides: ε-(LYRH)K10, ε-(LYH)K10, ε-(LYK)...
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| Format: | Thesis |
| Language: | English |
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2012
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| Online Access: | https://hdl.handle.net/10356/50471 |