Conjugation of antibody fragments to ferritin protein cage for targeted delivery to cancer cells.
Ferritin is engineered as a targeted carrier for therapeutic and diagnostic agents. It is a naturally occurring biomaterial and functions in iron homeostasis in various organisms. The ferritin in this study is a protein cage derived from an archaeon Archaeoglobus fulgidus with unique self-assembling...
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| Format: | Thesis |
| Language: | English |
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2012
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| Online Access: | http://hdl.handle.net/10356/50532 |