Translation termination mechanism studied by solution state NMR
Translation termination occurs when one of three stop-codons (UAA, UGA, or UAG) in mRNA reaches the ribosomal A site. In eukaryotes, class-I release factor (eRF1) directly recognizes all three stop-codons in the A site on the small ribosomal subunit and stimulates peptide release. N-domain of eRF1 p...
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Format: | Thesis |
Language: | English |
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2012
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Online Access: | https://hdl.handle.net/10356/50711 |