Characterization of pellino1 and pellino2 in toll-like receptor signaling
Pellino family proteins were first identified as interacting partners with kinase IRAK1 in TLR/IL-1R pathway. There are three Pellino isoforms in human cells, termed Pellino1, Pellino2 and Pellino3. They contain a FHA and a RING domain in the N- and C-terminus regions respectively. The major varianc...
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| Format: | Thesis |
| Language: | English |
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Nanyang Technological University
2012
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| Online Access: | http://hdl.handle.net/10356/50864 |