Studies of DNA-interacting properties of certain topological enzymes

Topoisomerases are topological enzymes that are involved in the regulation of DNA supercoiling. In this thesis, two of the type IIA topoisomerases, Topoisomerase II and DNA Gyrase, will be discussed and their DNA-interacting properties will be studied. Firstly, the change in topology of Kine...

Full description

Bibliographic Details
Main Author: Lee, Jasmine Yiqin
Other Authors: School of Physical and Mathematical Sciences
Format: Thesis
Language:English
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/10356/51880