Identification of microRNA targets for Isoforms of pro-apoptotic factor BIM.
BCL-2-interacting mediator of cell death (BIM) is a prominent regulator of the intrinsic apoptotic pathway. Aberrant BIM expression has been implicated in a multitude of diseases. Intriguingly, post-transcriptional regulation, modulated primarily by cis-elements in the 3’untranslated regions (UTRs),...
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Format: | Final Year Project (FYP) |
Language: | English |
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2013
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Online Access: | http://hdl.handle.net/10356/52294 |