Establishing two transgenic mouse cell lines for future studies on X chromosome inactivation : a red Xi in live cells and a silenced GFP on the Xi.
X chromosome inactivation (XCI) is a classic example of dosage compensation in the female eutherians. XCI is defined as a process in which one of the X chromosomes in a XX female cell is stochastically chosen to be inactivated. Consequently, a balance in X-linked gene dosages between female and male...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2013
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| Online Access: | http://hdl.handle.net/10356/53818 |