Design and application of cyclic-di-GMP biosensors.
Cyclic‐di‐GMP is an important bacterial secondary messenger molecule that regulates motility, virulence and biofilm formation in many pathogenic bacteria. This messenger molecule is synthesized from cellular GTP by diguanylate cyclase (DGC) and hydrolyzed by phosphodiesterases (PDE) to form...
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Format: | Thesis |
Language: | English |
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2014
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Online Access: | http://hdl.handle.net/10356/55277 |