Alternative pre-mRNA splicing in mammalian nervous system

Alternative pre-mRNA splicing provides a potent post-transcriptional mechanism for diversifying the transcriptome and regulating gene expression levels. Polypyrimidine tract-binding protein (Ptbp1) is a global regulator of alternative splicing affecting approximately a quater of the neuron-specific...

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Bibliographic Details
Main Author: Yap, Karen Lin Choo
Other Authors: School of Biological Sciences
Format: Thesis
Language:English
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/10356/55438