Novel functions of the oncofetal HMGA2 protein in genome stability
The non-histone chromatin factor HMGA2 (High Mobility Group AT-hook 2), which contains three AT-hook motifs as independent DNA binding domains, is normally expressed in ES cells and during embryonic/fetal development. In this study, I investigated its function in protecting the stalled replication f...
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格式: | Thesis |
语言: | English |
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2014
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在线阅读: | http://hdl.handle.net/10356/55737 |