Novel functions of the oncofetal HMGA2 protein in genome stability
The non-histone chromatin factor HMGA2 (High Mobility Group AT-hook 2), which contains three AT-hook motifs as independent DNA binding domains, is normally expressed in ES cells and during embryonic/fetal development. In this study, I investigated its function in protecting the stalled replication f...
Main Author: | Yu, Haojie |
---|---|
Other Authors: | Peter Droge |
Format: | Thesis |
Language: | English |
Published: |
2014
|
Subjects: | |
Online Access: | http://hdl.handle.net/10356/55737 |
Similar Items
-
Cell-based high-throughput compound screening reveals functional interaction between oncofetal HMGA2 and topoisomerase I
by: Peter, Sabrina, et al.
Published: (2018) -
Oncofetal HMGA2 as a key regulator of telomere stability through control of DNA topology
by: Dharshana, Ramani Priya
Published: (2018) -
Oncofetal HMGA2 effectively curbs unconstrained (+) and (−) DNA supercoiling
by: Zhao, Xiaodan, et al.
Published: (2018) -
Chromatin structuring factor HMGA2 controls subtelomere stability and cancer chemosensitivity
by: Syed Moiz Ahmed
Published: (2020) -
Functional role of HMGA2 in DNA repair and genome stability of HeLa cells.
by: Kok, Chun Peng.
Published: (2009)