Mathematical model of activation of transforming growth factor - β1 with application to liver fibrosis progression
Transforming growth factor-β1 (TGF-β1) plays important roles in diverse cellular programs and extracellular activation of TGF-β1 from its latent form is an important stage in its physiological regulation. Plasmin has long been accepted as an activator of TGF-β1, but experimental data using in vivo f...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
2014
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10356/60570 |