Development of oligonucleotides-based inhibitors and studies of the topological phenomenon of mobius DNA

With the aim of exploring new properties and applications of DNA enzymes such as Topoisomerase I and DNA ligase, during this study, the discovery of (1) oligonucletides-based DNA ligase inhibitors and (2) Topological phenomenon of Topoisomerase I and Mobius circular DNA were achieved. In Chap...

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Bibliographic Details
Main Author: Ng, Magdeline Tao Tao
Other Authors: Li Tianhu
Format: Thesis
Language:English
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10356/62168