Study of Xist-mediated gene silencing using iXist

X Chromosome Inactivation (XCI) is an example of dosage compensation in mammals in which one of the X chromosomes in females is inactivated to balance the gene dosage between males and females. This process is dependent on a long non-coding RNA (lncRNA) called Xist. Previous report showed that Xist...

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Bibliographic Details
Main Author: Tan, Jin Da
Other Authors: Zhang Li Feng
Format: Final Year Project (FYP)
Language:English
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10356/63463