CRISPR/Cas9-system mediated deletion of the Neurofibromin 1 tumour suppressor gene in human gliomas
Conventional therapies to treat glioblastoma multiforme (GBM) are unable to completely eliminate tumour cells and rapid emergence of post-therapeutic tumour lesions results in high patient mortality rates. Clinical observations have suggested the presence of a proneural to mesenchymal transition (PM...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2015
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| Online Access: | http://hdl.handle.net/10356/63811 |