Identification of AHR and hypoxia co-regulated immune target genes as potential factors of inflammation-driven oncogenesis
The transcription factors AHR and HIFs dimerize with the common co-activator ARNT during adaptive responses to xenobiotic exposure and oxygen tension. This cross-talk may subsequently modulate inflammation and/or physiological adaptation via immune cellular survival and maturation. Dysregulation of...
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| Format: | Thesis |
| Language: | English |
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2015
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| Online Access: | http://hdl.handle.net/10356/65300 |