Understanding Aβ dimer/inhibitor interactions from computer simulations

Aggregation of the Amyloid β-protein (Aβ) peptide is one key feature in Alzheimer’s disease (AD). Growing evidence supports that Aβ oligomers are the major causative agents leading to neural cell death in Alzheimer’s disease. The polyphenol (-)-epigallocatechin gallate (EGCG) and 1,4-naphthoquinon-2...

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Bibliographic Details
Main Author: Zhang, Tong
Other Authors: Mu Yuguang
Format: Thesis
Language:English
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10356/65311