Use of a promiscuous biotin ligase to identify partners of the CRTC transcription factor

CREB is an important transcription factor that is regulated in part by the CRTC family of cofactors. CRTCs work in tandem with CREB to mediate various metabolic processes, such as promoting gluconeogenesis in response to increased glucagon levels. CRTC1 in particular is highly expressed in the brai...

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Bibliographic Details
Main Author: Nai, Rui Si
Other Authors: Mark Stephen Featherstone
Format: Final Year Project (FYP)
Language:English
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10356/65366