The study of dopamine metabolism with LRRK2 variants in Parkinson’s disease

Background: Parkinson's disease (PD) is a neurodegenerative disease in which symptoms typically appear when a loss of dopaminergic (DA) neurons causes dopamine levels to fall significantly. Leucine rich repeat kinase 2 (LRRK2) gene mutations are the most common genetic cause of PD. Dopamine dec...

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Bibliographic Details
Main Author: Kwok, Wei Hao
Other Authors: Zhao Yi
Format: Final Year Project (FYP)
Language:English
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10356/65657