Characterization of progesterone receptor isoform-selective activities of progesterone receptor modulators in breast cancer cells.
This study reveals the effects of progesterone receptor modulators (PRMs) mediated by PR isoforms in PR-transfected MDA-MB-231 cells. Through PR-A and PR-B, PRMs CP8668, AED and Dex-Mes exhibited progesterone agonist effect in which they induced cell spreading, focal adhesion, cell migration and inh...
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| Format: | Thesis |
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2008
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| Online Access: | http://hdl.handle.net/10356/6571 |