Interaction of Presenilin-1 C-terminal fragment with FKBP38

The gene product of familial Alzheimer’s disease, presenilin-1 (PS-1), is a polytopic protein consisting of eight transmembrane domains and is predominantly localized in the endoplasmic reticulum (ER) and Golgi apparatus. Previous studies have shown that FK506 binding protein 38 is the direct intera...

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Bibliographic Details
Main Author: Tai, Jeff Seng Thong
Other Authors: Yoon, Ho Sup
Format: Thesis
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/10356/6572