The activation states of LFA-1 (alphaL beta2) and related integrins
Leukocyte integrins (beta2 integrins) are involved in many immune and inflammatory responses. The key function of leukocytes is impaired in the LAD-I patients due to the defects in beta2 gene. Two missense LAD-1 mutations N329S and R571C were studied. alphaLbeta2N329S can mediate constitutive adhesi...
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| Format: | Thesis |
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2008
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| Online Access: | https://hdl.handle.net/10356/6577 |