Identifying T helper cells involved in B cell immunoglobulin class-switching to IgE and comparing T helper cells of systemic or mucosal origin
IgE antibodies are key players in allergic diseases. The production of IgE requires B and T cell interactions and the cytokine IL-4. The main goal of this thesis is to identify the CD4+ T cell populations that mediate B cell class switching to IgE. For this work we used mice with defined antigen spe...
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| Format: | Thesis |
| Language: | English |
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2015
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| Online Access: | http://hdl.handle.net/10356/65855 |