Optimization of the CRISPR/Cas9 system for excision of genomic regions in human cancer cell cultures

In recent years, the role of chromatin interactions in regulating gene expression has been intensively studied. Although much insight into the factors and mechanisms underlying the establishment and maintenance of chromatin loops has been gained, there still remains much to be understood. In this th...

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Bibliographic Details
Main Author: Tng, Jia Qi
Other Authors: Melissa Jane Fullwood
Format: Final Year Project (FYP)
Language:English
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10356/67362