Characterization of regulatory mechanisms for BIM exon 3 alternative splicing
BCL-2-interacting mediator of cell death (BIM) is a proapoptotic member of the BCL-2 protein family. BIM upregulation is required for tyrosine kinase inhibitor (TKI)-mediated cell death in many kinase-driven cancers including chronic myeloid leukemia (CML) and epidermal growth factor receptor mutate...
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| Format: | Thesis |
| Language: | English |
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2017
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| Online Access: | http://hdl.handle.net/10356/69548 |