Truncation of Cas9 protein for high performance target-specific genome engineering
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR associated proteins (Cas) system has emerged as a genome engineering tool with the programmable guide RNA sequence for specific gene targeting. However, for lentiviral based in vivo testing and engineering such as adeno-as...
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| Format: | Thesis |
| Language: | English |
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2017
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| Online Access: | http://hdl.handle.net/10356/72369 |