Structural studies on proteins involved in human telomere maintenance

In order to sustain genomic stability and cellular viability, the ends of linear eukaryotic chromosomes are capped and protected by telomeres. The mechanism by which the length of telomeric DNA is maintained involves a specialized reverse transcriptase, called telomerase. This thesis focuses on t...

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Bibliographic Details
Main Author: Ufuk Borucu
Other Authors: Daniela Rhodes
Format: Thesis
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10356/72778