Structural plasticity of BCL-2 family proteins and its functional implication in apoptosis
Dysregulated apoptosis has been implicated in the development of several diseases including cancer and neurodegenerative diseases. Bcl-2 family proteins regulate mitochondrial apoptosis through homo- and hetero-dimerization between pro- and anti-apoptotic Bcl-2 proteins. The first part of this stu...
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Format: | Thesis |
Language: | English |
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2018
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Online Access: | http://hdl.handle.net/10356/73522 |