Nucleic acid structures containing g-quadruplex and duplex motifs : a structural study and potential targeting approach
Guanine-rich nucleic acid sequences have the propensity to assume four-stranded structures known as G-quadruplex. G-quadruplex-forming sequences were identified at important regulatory regions in the human genome such as the telomere, gene promoter, and 5’-untranslated region of mRNA. Important biol...
Main Author: | |
---|---|
Other Authors: | |
Format: | Thesis |
Language: | English |
Published: |
2018
|
Subjects: | |
Online Access: | http://hdl.handle.net/10356/73601 |