Validating the involvement of AGFG1 in X chromosome inactivation through CRISPR/Cas9 genome editing
X chromosome inactivation (XCI) is a phenomenon that occurs in mammals, whereby X chromosome is silenced in female to balance the X-linked gene dosage. Although XCI and the role of non-coding RNA Xist in XCI have been intensively studied, the exact mechanism and modulators of XCI are largely unclear...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2018
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| Online Access: | http://hdl.handle.net/10356/74150 |