Modeling MELAS-associated cardiac defects using patient-specific iPSC-derived cardiomyocytes and cardiac organoids

Mitochondrial diseases are a diverse family of maternally-inherited disorders that often result from mitochondrial DNA (mtDNA) mutations. These disorders are mostly heterogeneous and manifest as a broad spectrum of clinical phenotypes among patients. In this study, we will be utilising patient-speci...

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Bibliographic Details
Main Author: Phua, Qian Hua
Other Authors: Soh Boon Seng
Format: Final Year Project (FYP)
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/74163