Towards X-ray crystallographic characterization of nucleosome interactions with linker histones, FOXA proteins and high mobility group N factors
In the eukaryotic cell nucleus, genetic material is packaged into chromatin, consisting of arrays of nucleosomes that can be densely compacted. The three-dimensional organization of chromatin imparts a sophisticated temporally and spatially controlled regulation of accessibility to the genes. Global...
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| Format: | Thesis |
| Language: | English |
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2018
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| Online Access: | http://hdl.handle.net/10356/74380 |