Using human induced pluripotent stem cells to investigate the roles of astrocytes in spinal muscular atrophy

Spinal muscular atrophy (SMA) is a neuromuscular disease caused by the mutation of SMN1 gene and which is characterized by the selective degeneration of lower motor neurons. Through the years, it has become more evident that SMA is not solely a disease of the lower motor neurons, but other cell type...

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Bibliographic Details
Main Author: Loh, Sharon Jia Hui
Other Authors: Albert I. Chen
Format: Thesis
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/74828