Structural and biochemical study of kindlin-3 in integrin activation
Kindlin-3, a member of the FERM family proteins, functions as an adaptor between cell membrane and cytoskeleton proteins. It is mostly expressed in hematopoietic and endothelial cells. Leukocyte adhesion deficiency syndrome (LAD-III) in human has been linked to the expression of mutant Kindlin-3 pro...
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| Format: | Thesis |
| Language: | English |
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2018
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| Online Access: | http://hdl.handle.net/10356/75441 |