Biochemical and structural analysis of shelterin subcomplexes

Telomeric chromatin consists of tandem ‘TTAGGG’ DNA repeats that associate with a telomere-specific complex, known as shelterin. Shelterin has an indispensable role in telomere length homeostasis and protection against genomic instability arising from erroneous DNA damage responses. Shelterin collec...

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Bibliographic Details
Main Author: Inian, Oviya
Other Authors: Daniela Rhodes
Format: Thesis
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/75683