Biochemical and structural analysis of shelterin subcomplexes
Telomeric chromatin consists of tandem ‘TTAGGG’ DNA repeats that associate with a telomere-specific complex, known as shelterin. Shelterin has an indispensable role in telomere length homeostasis and protection against genomic instability arising from erroneous DNA damage responses. Shelterin collec...
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Format: | Thesis |
Language: | English |
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2018
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Online Access: | http://hdl.handle.net/10356/75683 |