Targeting adenosine-2 B receptor : a potential metabolic immune checkpoint
Adenosine is an anti-inflammatory and immunosuppressive metabolite that binds to the adenosine receptors (AR) - A1R, A2AR, A2BR and A3R. Adenosine immunosuppression is mediated via A2Rs, with A2BR only activated by high adenosine concentration such as within solid tumor microenvironments (TME). A...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2019
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| Online Access: | http://hdl.handle.net/10356/77108 |