CRISPR-based epigenome editing for targeted gene regulation

The discovery of CRISPR (clustered regularly interspaced short palindromic repeats) gene editing technology has increased the repertoire of methods to target and test specific gene functions. CRISPR-Cas system has been modified by fusing epigenetic modifiers to a “dead” Cas9 endonuclease (dCas9) to...

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Bibliographic Details
Main Author: Leong, Jonavan Jing
Other Authors: Amartya Sanyal
Format: Final Year Project (FYP)
Language:English
Published: 2019
Subjects:
Online Access:http://hdl.handle.net/10356/79000