An internal ribosome entry site (IRES) mutant library for tuning expression level of multiple genes in mammalian cells

An internal ribosome entry site (IRES) mutant library for tuning expression level of multiple genes in mammalian cells

A set of mutated Encephalomyocarditis virus (EMCV) internal ribosome entry site (IRES) elements with varying strengths is generated by mutating the translation initiation codons of 10th, 11th, and 12th AUG to non-AUG triplets. They are able to control the relative expression of multiple genes over a...

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Bibliographic Details
Main Authors: Koh, Esther Y. C., Ho, Steven C. L., Mariati, Song, Zhiwei, Bi, Xuezhi, Bardor, Muriel, Yang, Yuansheng
Other Authors: Hendershot, Linda M.
Format: Journal Article
Language:English
Published: 2015
Online Access:https://hdl.handle.net/10356/79242
http://hdl.handle.net/10220/38558

Internet

https://hdl.handle.net/10356/79242
http://hdl.handle.net/10220/38558

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