dissectHMMER: a HMMER-based score dissection framework that statistically evaluates fold-critical sequence segments for domain fold similarity

Background: Annotation transfer for function and structure within the sequence homology concept essentially requires protein sequence similarity for the secondary structural blocks forming the fold of a protein. A simplistic similarity approach in the case of non-globular segments (coiled coils, low...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Wong, Wing-Cheong, Yap, Choon-Kong, Eisenhaber, Birgit, Eisenhaber, Frank
Weitere Verfasser: School of Computer Engineering
Format: Journal Article
Sprache:English
Veröffentlicht: 2015
Online Zugang:https://hdl.handle.net/10356/79276
http://hdl.handle.net/10220/38714