Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons

Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons

Previous studies have revealed a critical role for CREB-regulated transcriptional coactivator (CRTC1) in regulating neuronal gene expression during learning and memory. CRTC1 localizes to synapses but undergoes activity-dependent nuclear translocation to regulate the transcription of CREB target gen...

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Bibliographic Details
Main Authors: Ch'ng, Toh Hean, DeSalvo, Martina, Lin, Peter, Vashisht, Ajay, Wohlschlegel, James A., Martin, Kelsey C.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2015
Online Access:https://hdl.handle.net/10356/79343
http://hdl.handle.net/10220/38742

Internet

https://hdl.handle.net/10356/79343
http://hdl.handle.net/10220/38742

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