Type I IFN signaling in CD8– DCs impairs Th1-dependent malaria immunity

Type I IFN signaling in CD8– DCs impairs Th1-dependent malaria immunity

Many pathogens, including viruses, bacteria, and protozoan parasites, suppress cellular immune responses through activation of type I IFN signaling. Recent evidence suggests that immune suppression and susceptibility to the malaria parasite, Plasmodium, is mediated by type I IFN; however, it is uncl...

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Bibliographic Details
Main Authors: Varelias, Antiopi, Hertzog, Paul J., Kalinke, Ulrich, Montes de Oca, Marcela, James, Kylie R., Ammerdorffer, Anne, Edwards, Chelsea L., de Labastida Rivera, Fabian, Amante, Fiona H., Bunn, Patrick T., Sheel, Meru, Sebina, Ismail, Koyama, Motoko, Haque, Ashraful, Best, Shannon E., Gun, Sin Yee, Rénia, Laurent, Ruedl, Christiane, MacDonald, Kelli P.A., Hill, Geoffrey R., Engwerda, Christian R.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2014
Subjects:
DRNTU::Science::Medicine
Online Access:https://hdl.handle.net/10356/80006
http://hdl.handle.net/10220/20014

Internet

https://hdl.handle.net/10356/80006
http://hdl.handle.net/10220/20014

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