Mannitol enhances antibiotic sensitivity of persister bacteria in Pseudomonas aeruginosa biofilms

The failure of antibiotic therapies to clear Pseudomonas aeruginosa lung infection, the key mortality factor for cystic fibrosis (CF) patients, is partly attributed to the high tolerance of P. aeruginosa biofilms. Mannitol has previously been found to restore aminoglycoside sensitivity in Escherichi...

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Bibliographic Details
Main Authors: Rice, Scott A., Barraud, Nicolas, Buson, Alberto, Jarolimek, Wolfgang
Other Authors: Beloin, Christophe
Format: Journal Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/80009
http://hdl.handle.net/10220/18797