Plasma proteome coverage is increased by unique peptide recovery from sodium deoxycholate precipitate

Plasma proteome coverage is increased by unique peptide recovery from sodium deoxycholate precipitate

The ionic detergent sodium deoxycholate (SDC) is compatible with in-solution tryptic digestion and LC-MS/MS-based shotgun proteomics by virtue of being easy to separate from the peptide products via precipitation in acidic buffers. However, it remains unclear whether unique human peptides co-precipi...

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Bibliographic Details
Main Authors: Serra, Aida, Zhu, Hongbin, Gallart-Palau, Xavier, Park, Jung Eun, Ho, Hee Haw, Tam, James P., Sze, Siu Kwan
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2016
Subjects:
Trypsin digestion
Plasma proteome
Mass spectrometry
Shotgun proteomics
Sodium deoxycholate
Online Access:https://hdl.handle.net/10356/80250
http://hdl.handle.net/10220/40445

Internet

https://hdl.handle.net/10356/80250
http://hdl.handle.net/10220/40445

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