Development of immune-modulatory RNAS to regulate RIG-I-like receptors mediated antiviral immune response for therapy and vaccination
Retinoic Acid-Inducible Gene I (RIG-I) is a cytosolic pattern recognition receptor (PRR) involved in initiating host defence response against viruses. RIG-I distinguishes between self and foreign nucleic acids by recognising chemical features not found in endogenous cytoplasmic RNA. RIG-I exhibits...
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| Format: | Thesis |
| Language: | English |
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2019
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| Online Access: | https://hdl.handle.net/10356/81015 http://hdl.handle.net/10220/47467 |