N-terminal domain of PB1-F2 protein of influenza A virus can fold into amyloid-like oligomers and damage cholesterol and cardiolipid containing membranes

N-terminal domain of PB1-F2 protein of influenza A virus can fold into amyloid-like oligomers and damage cholesterol and cardiolipid containing membranes

PB1-F2 protein is a factor of virulence of influenza A viruses which increases the mortality and morbidity associated with infection. Most seasonal H1N1 Influenza A viruses express nowadays a truncated version of PB1-F2. Here we show that truncation of PB1-F2 modified supramolecular organization of...

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Bibliographic Details
Main Authors: Ajjaji, Dalila, Richard, Charles-Adrien, Mazerat, Sandra, Chevalier, Christophe, Vidic, Jasmina
Other Authors: School of Materials Science & Engineering
Format: Journal Article
Language:English
Published: 2016
Subjects:
PB1-F2-Membrane interaction
Influenza A viruses
Amyloid-like protein structures
Cholesterol
Cardiolipin
Online Access:https://hdl.handle.net/10356/81154
http://hdl.handle.net/10220/40672

Internet

https://hdl.handle.net/10356/81154
http://hdl.handle.net/10220/40672

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