Conditional N-WASP knockout in mouse brain implicates actin cytoskeleton regulation in hydrocephalus pathology

Conditional N-WASP knockout in mouse brain implicates actin cytoskeleton regulation in hydrocephalus pathology

Cerebrospinal fluid (CSF) is produced by the choroid plexus and moved by multi-ciliated ependymal cells through the ventricular system of the vertebrate brain. Defects in the ependymal layer functionality are a common cause of hydrocephalus. N-WASP (Neural-Wiskott Aldrich Syndrome Protein) is a brai...

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Bibliographic Details
Main Authors: Jain, Neeraj, Lim, Lee Wei, Tan, Wei Ting, George, Bhawana, Makeyev, Eugene, Thanabalu, Thirumaran
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2015
Subjects:
Actin cytoskeleton
Hydrocephalus
N-WASP
Cilia
Astrogliosis
Cerebral ventricles
Online Access:https://hdl.handle.net/10356/81206
http://hdl.handle.net/10220/39154

Internet

https://hdl.handle.net/10356/81206
http://hdl.handle.net/10220/39154

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