Identifying and engineering promoters for high level and sustainable therapeutic recombinant protein production in cultured mammalian cells

Promoters are essential on plasmid vectors to initiate transcription of the transgenes when generating therapeutic recombinant proteins expressing mammalian cell lines. High and sustained levels of gene expression are desired during therapeutic protein production while gene expression is useful for...

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Detalhes bibliográficos
Principais autores: Ho, Steven C. L., Yang, Yuansheng
Outros Autores: School of Chemical and Biomedical Engineering
Formato: Journal Article
Idioma:English
Publicado em: 2016
Assuntos:
Acesso em linha:https://hdl.handle.net/10356/81399
http://hdl.handle.net/10220/40783