The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production

Dengue virus NS5 is the most highly conserved amongst the viral non-structural proteins and is responsible for capping, methylation and replication of the flavivirus RNA genome. Interactions of NS5 with host proteins also modulate host immune responses. Although replication occurs in the cytoplasm,...

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Bibliografiska uppgifter
Huvudupphovsmän: Chan, Kitti W. K., Tay, Moon Y. F., Smith, Kate, Ng, Ivan H. W., Zhao, Yongqian, Ooi, Eng Eong, Lescar, Julien, Luo, Dahai, Jans, David A., Forwood, Jade K., Vasudevan, Subhash G.
Övriga upphovsmän: Rey, Félix A.
Materialtyp: Journal Article
Språk:English
Publicerad: 2017
Ämnen:
Länkar:https://hdl.handle.net/10356/83021
http://hdl.handle.net/10220/42375